Published Papers


Reciprocal regulation of actomyosin organization and contractility in nonmuscle cells by tropomyosins and alpha-actinins

Hu S, Grobe H, Guo Z, Wang YH, Doss BL, Pan M, Ladoux B, Bershadsky AD, Zaidel-Bar R. (2019) Molecular Biology of the Cell. Jul 22;30(16):2025-2036.

Salmonella biofilms program innate immunity for persistence in Caenorhabditis elegans

Desai SK, Padmanabhan A, Harshe S, Zaidel-Bar R, Kenney LJ. (2019 ) Proc Natl Acad Sci U S A. Jun 18;116(25):12462-12467.

From cell shape to cell fate via the cytoskeleton - Insights from the epidermis

Luxenburg C, Zaidel-Bar R. (2019) Exp Cell Res. May 15;378(2):232-237.

The RhoGAP SPV-1 regulates calcium signaling to control the contractility of the Caenorhabditis elegans spermatheca during embryo transits

Bouffard J, Cecchetelli AD, Clifford C, Sethi K, Zaidel-Bar R, Cram EJ. (2019 ) Mol Biol Cell. Mar 21;30(7):907-922.


Principles of Actomyosin Regulation In Vivo

Agarwal P, Zaidel-Bar R.  (2018) Trends Cell Biol. Oct 29. pii: S0962-8924(18)30161-2.

Syncytial germline architecture is actively maintained by contraction of an internal actomyosin corset

Priti A, Ong H-T, Toyama Y, Padmanabhan A, Dasgupta S, Krajnc M, Zaidel-Bar R. (2018) Nature Communications DOI: 10.1038/s41467-018-07149-2

The myosin light-chain kinase MLCK-1 relocalizes during Caenorhabditis elegans ovulation to promote actomyosin bundle assembly and drive contraction

Kelly CA, Wirshing ACE, Zaidel-Bar R, Cram EJ. (2018) Molecular Biology of the Cell 29(16):1975-1991

Spatially modulated ephrinA1:EphA2 signaling increases local contractility and global focal adhesion dynamics to promote cell motility

Chen Z, Oh D, Biswas KH, Yu CH, Zaidel-Bar R*, Groves JT. (2018) Proc Natl Acad Sci U S A. 115(25):E5696-E5705. *corresponding author


Stretch-induced actomyosin contraction in epithelial tubes: Mechanotransduction pathways for tubular homeostasis

Sethi K, Cram EJ, Zaidel-Bar R. (2017) Semin Cell Dev Biol. pii: S1084-9521(17)30176-3.

Plastin increases cortical connectivity to facilitate robust polarization and timely cytokinesis

Ding W-Y, Ong H-T, Hara Y, Wongsantichon J, Toyama Y, Robinson R, Nédélec F, Zaidel-Bar R. (2017) Journal of Cell Biology 216(5): 1371-1386.

Early events in the assembly of E-cadherin adhesions

Biswas KH, Zaidel-Bar R. (2017) Experimental Cell Research Feb 22. pii: S0014-4827(17)30090-3.

Long range self-organization of cytoskeletal myosin-II filament stacks

Hu S, Dasbiswas K, Guo Z, Tee Y-H, Thiagarajan V, Hersen P, Chew T-L, Safran SA, Zaidel-Bar R* and Bershadsky AD (2017) Nature Cell Biology 19(2):133-141. *corresponding author

Nanoscale architecture of cadherin-based adhesions

Bertocchi C, Wang Y, Ravasio A, Hara Y, Wu Y, Sailov T, Baird MA, Davidson MW, Zaidel-Bar R, Toyama Y, Ladoux B, Mege RM, and Kanchanawong P. (2017) Nature Cell Biology 19(1):28-37.

Non-junctional E-Cadherin Clusters Regulate the Actomyosin Cortex in the C. elegans Zygote

Padmanabhan A, Ong H-T and Zaidel-Bar R. (2017) Current Biology 27:1-10.


Formin-mediated actin polymerization at cell-cell junctions stabilizes E-cadherin and maintains monolayer integrity during wound repair

Vaman Rao M and Zaidel-Bar R. (2016) Molecular Biology of the Cell 27(18):2844-56.

Sustained α-catenin conformational activation at E-cadherin junctions in the absence of mechanical force

Biswas KH, Hartman KL, Zaidel-Bar R* and Groves JT*. (2016) Biophysical Journal 111(5):1044-52. 

*corresponding author

The AP-2 transcription factor APTF-2 is required for neuroblast and epidermal morphogenesis in Caenorhabditis elegans embryogenesis

Budirahardja Y, Tan PY, Doan T, Weisdepp P, Zaidel-Bar R. (2016) PLoS Genetics 12(5):e1006048.


E-cadherin junction formation involves an active kinetic nucleation process

Biswas KH, Hartman KL, Yu C-H, Harrison OJ, Song H, Smith AW, Huang WYC, Lin W-C, Guo Z, Padmanabhan A, Troyanovsky SM, Dustin ML, Shapiro L, Honig B, Zaidel-Bar R and Groves JT. (2015) PNAS 112(35):10932-7.    

There are four dynamically and functionally distinct populations of E-cadherin in cell junctions

Erami Z, Anannya O, Schwarz JP, Timpson P, Yao W, Zaidel-Bar R, and Anderson KI. (2015) Biology Open 4(11):1481-9.

Structured illumination microscopy reveals focal adhesions are composed of linear subunits

Hu S, Tee YH, Kabla A, Zaidel-Bar R, Bershadsky A, Hersen P. (2015) Cytoskeleton (Hoboken) 72(5):235-45.

Glycosyl phosphatidylinositol anchor biosynthesis is essential for maintaining epithelial integrity during Caenorhabditis elegans embryogenesis

Budirahardja Y, Doan T, and Zaidel-Bar R. (2015) Plos Genetics 11(3):e1005082.

Jack of all trades: functional modularity in adherens junctions

Padmanabhan A, Vaman Rao M, Yao W, and Zaidel-Bar R. (2015) Current Opinions in Cell Biology 36:32-40.

The contractome - a systems view of actomyosin contractility in non-muscle cells

Zaidel-Bar R, Gou Z, and Luxenburg C. (2015) Journal of Cell Science 128(12):2209-17.

Actin-delimited adhesion-independent clustering of E-cadherin forms the nanoscale building blocks of adherens junctions

Wu Y, Kanchanawong P, and Zaidel-Bar R. (2015) Developmental Cell 32(2):139-54.

Transient membrane localization of SPV-1 drives cyclical actomyosin contractions in the C. elegans spermatheca

Tan P-Y and Zaidel-Bar R. (2015) Current Biology 25(2):141-51.


E-cadherin adhesome complexity and robustness resolved by quantitative proteomics

Guo Z, Neilson LJ, Hang Z, Murray P, Zanivan S, and Zaidel-Bar R. (2014) Science Signaling 7(354), rs7.

Premetazoan origins and evolution of the cadherin adhesome

Murray P, and Zaidel-Bar R. (2014) Biology Open 3:1183-1195.

2013 and before

Cadherin adhesome components and interactions at a glance

Zaidel-Bar R. (2013) Journal of Cell Science 126:373-378.

A novel tool for the activation of endogenous diaphanous-related formins by light reveals thickening of stress fibers without an apparent increase in tension

Vaman Rao M. Chu P-H, Hahn KM, and Zaidel-Bar R (2013) Cytoskeleton (Hoboken) 70(7):394-407.

Regulation of Adherens Junction Dynamics by Phosphorylation Switches

Bertocchi C, Vaman Rao M, and Zaidel-Bar R. (2012) Journal of Signal Transduction, vol. 2012, Article ID 125295.

Tropomodulin Protects a-catenin-dependent Junctional-Actin Networks Under Stress during Epithelial Morphogenesis

Cox-Paulson EA, Walck-ShannonE, Lynch AM, Yamashiro S, Zaidel-Bar R, Eno CC, Ono S, Hardin J. (2012) Current Biology 21;22(16):1500-5.

Opening the floodgates: proteomics and the integrin adhesome

Geiger T, Zaidel-Bar R. (2012) Current Opinions in Cell Biology 24(5):562-8.

Loss of the RhoGAP SRGP-1 promotes the clearance of dead and injured cells in Caenorhabditis elegans

Neukomm LJ, Frei AP, Cabello J, Kinchen JM, Zaidel-Bar R, Ma Z, Haney LB, Hardin J, Ravichandran KS, Moreno S, Hengartner MO. (2011) Nature Cell Biology 13(1):79-86.

The switchable integrin adhesome

Zaidel-Bar R, Geiger B. (2010) Journal of Cell Science 123(9):1385-8.

The F-BAR domain of SRGP-1 facilitates cell-cell adhesion during C. elegans morphogenesis

Zaidel-Bar R, Joyce MJ, Lynch AM, Witte K, Audhya A, Hardin JD. (2010) Journal of Cell Biology 191(4):761-9.

Molting-specific downregulation of C. elegans body-wall muscle attachment sites: The role of RNF-5 E3 ligase

Zaidel-Bar R, Miller S, Broday L. (2010) Biochemical Biophysical Research Comm. 14;395(4):509-14.

Evolution of Complexity in the Integrin Adhesome

Zaidel-Bar R.  (2009) Journal of Cell Biology 186(3):317-21.

Temporal evolution of cell focal adhesions: experimental observations and shear stress profiles

Aroush DRB, Zaidel-Bar R, Bershadsky AD, Wagner HD. (2008) Soft Matter 4 (12):2410-2417

The C. elegans Zonula Occludens ortholog ZOO-1 cooperates with the cadherin-catenin complex to recruit actin during epidermal morphogenesis

Lockwood C, Zaidel-Bar R, Hardin JD. (2008) Current Biology 18(17):1333-7.

Functional atlas of the integrin adhesome

Zaidel-Bar R, Itzkovitz S, Ma’ayan A, Iyengar R, Geiger B. (2007) Nature Cell Biology 9(8):858-67.

A paxillin tyrosine phosphorylation switch regulates the assembly and form of cell-matrix adhesions

Zaidel-Bar R, Milo R, Kam Z, Geiger B. (2007) Journal of Cell Science 120(Pt1):137-48.

Polarized down-regulation of the paxillin-p130CAS-Rac1 pathway induced by shear flow

Zaidel-Bar R, Kam Z, Geiger B. (2005) Journal of Cell Science 118(Pt17):3997-4007.

Hierarchical assembly of cell-matrix adhesion complexes

Zaidel-Bar R, Cohen M, Addadi L, Geiger B. (2004) Biochemical Society Transactions 32(Pt3):416-20.

Early molecular events in the assembly of matrix adhesions at the leading edge of migrating cells

Zaidel-Bar R, Ballestrem C, Kam Z, Geiger B. (2003) Journal of Cell Science 116(Pt22):4605-13.